Learn about epigenetics, epigenomics and the histone code, and techniques and protocols to study these changes. Protocols and links on DNA methylation specific PCR, chromatin immunoprecipitation, microarray, bisulfite DNA, 5-aza-2'-deoxycytidine treatments and sodium bisulfite DNA sequencing.

Transcriptional repression is an essential mechanism in the precise control of gene expression. Transcriptional repressor proteins associate with their target genes either directly through a DNA-binding domain or indirectly by interacting with other DNA-bound proteins.